I often have a burning sensation in my vagina after my partner has ejaculated. My health care provider suggested I may have a semen allergy. Does a semen allergy affect the ability to get pregnant?
Answer From Chandra C. Shenoy, M.D.
Semen allergy, also called seminal plasma hypersensitivity, happens when you have a harmful immune system reaction to proteins in semen. This condition is not common. Semen allergy isn’t a direct cause of infertility.
Symptoms of semen allergy include a change in skin color, burning and swelling where semen contacts the skin or vaginal tissues. Some people may have a whole-body response, including hives, itching and difficulty breathing.
If you have any of these symptoms, see your health care provider. Your provider may do skin testing to see if you have a semen allergy.
Treatment to make you less sensitive to your partner’s semen may allow you to get pregnant naturally. Another option is intrauterine insemination (IUI), which uses sperm washed free of semen proteins to prevent a reaction. For those with a severe sensitivity to semen, assisted reproductive technology, such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI), may be an option for pregnancy.
With
Chandra C. Shenoy, M.D.
There is a problem with
information submitted for this request. Review/update the
information highlighted below and resubmit the form.
Women’s health topics – straight to your inbox
Get the latest information from our Mayo Clinic experts on women’s health topics, serious and complex conditions, wellness and more. Click to view a preview and subscribe below.
To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt out of email communications at any time by clicking on the unsubscribe link in the email.
Thank you for subscribing!
You’ll soon start receiving the latest Mayo Clinic health information you requested in your inbox.
Sorry something went wrong with your subscription
Please, try again in a couple of minutes
Feb. 19, 2022
.